Log In|Sign Up
EN
The J1-4 regions were replaced with a J558 H10 family promoter, the H10 split leader sequence, a rearranged human heavy chain sequence of the HIV-1 antibody 4E10 (a self-/polyreactive, anti-gp41 BnAb) and a floxed neomycin resistance (neo) cassette. Cre-mediated recombination removed the neo cassette. (J:205708)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
