The coding sequence of exon 2 was replaced with a loxP site, lacZ gene, FRT-flanked neomycin resistance cassette, loxP site and polyadenylation sequence. Western blot analysis confirmed the absence of protein expression in the serum. (J:206120)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count