Exon 2 and 3 were replaced with a full-length cDNA containing nucleotide substitutions that result in the amino acid substitution of cysteine for phenylalanine at position 350 (F350C) fused to EGFP and followed by a floxed neomycin ressitance cassette. Flp-mediated recombination removed the selection cassette. (J:205754)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Nucleotide substitutions
--
1
6
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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