Homologous recombination was employed to insert an IRES-cre/ERT2-Frt-neo-Frt cassette 259 bp downstream of the stop codon of the Foxl2 gene. Chimeras were bred to C57BL/6 mice, and F1 animals were crossed to flp-expressing mice to delete the neo marker. (J:206011)
Basic Information
(C57BL/6NTac x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count