A lox71 site, lacZ gene, polyadenylation sequence, FRT-flanked neomycin resistance cassette and loxP site replaced the coding sequence from exon 1 through 5. Western blot analysis confirmed the absence of protein expression in the hypothalamic suprachiasmatic nucleus. (J:205653)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count