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EN
A BAC (RP11-729B4) containing the human MS4A1 (hCD20) locus was modified by insertion of an IRES-cre/ERT2 (cre recombinase-mutated human estrogen receptor ligand-binding domain fusion) cassette into the 3' untranslated region of the gene. The modified BAC vector was used to generate a transgene that expresses a tamoxifen-inducible cre specifically in B cells. MS4A1 is also expressed from this allele. Line numbers are not available. (J:184524)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
