A self-excising neomycin resistance cassette replaced 2857 bp spanning between exon 5 of Duoxa2 to coding exon 5 of Duoxa1. The final allele lacks the neomycin resistance cassette. Mice lack DUOX-based NADPH oxidase activity. (J:205329)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Intergenic deletion, Intragenic deletion
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11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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