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An 852 bp fragment of intron 1 of the mouse Cdx2 gene containing a neural specific enhancer was cloned upstream of a cre recombinase expression cassette. The cre cassette contains an Hsp68 minimal promoter, the cre recombinase open reading frame and the SV40 polyadenylation sequences. This construct was injected into (C57BL/6 x C3H) oocytes. Thirteen F0 founders were obtained with 8 testing positive for cre activity. A single male, R337, was bred to a wild type B6 female. (J:204467)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
