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A targeting construct with an Frt-flanked neo selection cassette 3' of the cre/ERT2 sequence was used for homologous recombination in ES cells. Cre recombinase was inserted into the ATG site in exon 1 of the Kit locus. Germline transmission of the allele was achieved by crossing to C57BL/J mice. (J:204737)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
