Exons 5, 6, and 7 were flanked by loxP sites and an FRT flanked selection cassette was inserted. Properly targeted mice were bred to mice expressing flp recombinase in order to excise the selection cassette. (J:200083)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count