A loxA1 site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 5' loxA1 site was inserted upstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 1 floxed. (J:179977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count