An IRES-LacZ gene trap cassette followed by an FRT flanked neo cassette and loxP site were inserted after the first three nucleotides of exon 2. RT-PCR with primers flanking exon 2 confirmed loss of transcripts in hearts of postnatal day 21 homozygous mice. (J:203454)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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