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EN
The targeting construct inserted between the Jalpha and C alpha exons four polyadenylation sequences, a 1.8 kb of upstream regulatory sequence, the Valpha14 promoter, a leader sequence, a floxed stop cassette, the sequence for the Valpha14 and Jalpha18 invariant (Valpha14i) arrangement expressed in most NKT cells and a 0.2 kb intronic sequence. This insertion abolishes TCRalpha expression. (J:201417)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
