An FRT flanked neo cassette was inserted in intron 3 upstream of loxP sites inserted in intron 3 and in intron 8. The selection cassette was subsequently deleted by crossing to a b-actin FLP mouse strain. Exons 4 to 8 were thus flanked by loxP sites. (J:204354)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count