A loxP site was inserted upstream of exon 1. A floxed neomycin resistance cassette was inserted downstream of exon 2. Cre-mediated recombination removed the neomycin resistance cassette and left exons 2 and 3 floxed. (J:204032)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count