The myelin basic protein promoter drives expression of a myc-tagged mutant Cadm4 transcript lacking the entire cytoplasmic domain. This functions as a dominant negative mutation. Western blot analysis demonstrated strong expression in the sciatic nerve. (J:199632)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count