Log In|Sign Up
EN
A floxed corresponding cDNA with a polyadenylation sequence was inserted upstream of exon 16. An IRES, lacZ and polyadenylation sequence followed by an FRT-flanked neomycin resistance cassette replaced exon 17. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed the cDNA. Western blot analysis confirmed the absence of protein expression in E18 embryos. (J:203073)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
