This transgene contains the MMTV promoter, the 3' of human growth hormone exons 4 and 5, and the human ERBB2 cDNA with the ATG removed. The transgene integrated at a single site on chromosome 6 and quantitative PCR analysis suggests a transgene copy number of 30-50. (J:90202)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count