The mutagenic insertion and chromosome engineering resource (MICER) 5' hprt vector clone MHPN117k13 was used to insert a loxP site at the 5' end of the type II keratin cluster (Krt1c) upstream of Krt80 (between Krt80 and Krt7). This clone contains an insert of 6 kb spanning 101,202,450-101,208,417 bp on chromosome 15 (genome assembly unknown), and includes the tyrosinase (Tyr) coat color gene, an HPRT mini-gene, a loxP site, and a neomycin resistance gene cassette. (J:153804)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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