An FRT-flanked neomycin cassette in intron 3, along with loxP sites in intron 2 and 3' of Frt site were incorporated into the genome. Flpe-mediated excision removed the neomycin cassette, leaving exon 3 floxed. (J:199365)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count