The targeting construct introduced into the locus a splice acceptor sequence, floxed neomycin resistance STOP (4x polyadenylation sequence) cassette, fusion of human TMPRSS2 (exon 1) and ERG (exon 4), IRES, nuclear localized EGFP and polyadenylation sequence. (J:200002)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count