A floxed STOP cassette was inserted upstream of the coding sequence. Cre-mediated recombination removed the floxed STOP cassette and restored expression. Western blot analysis confirmed normal protein expression. (J:199647)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count