Two loxP sites were inserted flanking exon 3, and a FRT-flanked neomycin cassette was inserted in intron 2. Flp recombinase mediated recombination removed neomycin cassette. (J:202213)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count