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EN
ENU mutagenesis induced a T to C mutation in the splice donor consensus site of exon 21; Chr19: 6,848,180 (- strand) (build NCBI38/mm10). The point mutation results in a 5 nt deletion in the transcript and a frame-shift with a predicted premature termination at codon 1286. Western blot analysis confirmed the absence of protein expression in the spleen, thymus, lymph nodes and kidney. (J:230618)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
