A loxP511site and loxP site were inserted upstream of exon 2 and an FRT flanked neo cassette, loxP site and loxP2722 site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. This allele is designed to permit recombination mediated cassette exchange. (J:199462)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count