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EN
The fDTR transgene was designed with a loxP-flanked alkaline phosphatase-polyadenylation signal upstream of a human diphtheria toxin receptor (DTR; heparin-binding epidermal growth factor-like growth factor (HBEGF)) under the transcriptional control of the murine calcium/calmodulin-dependent protein kinase II alpha (CamKIIalpha) promoter. Lines A and B were generated with line B exhibiting reduced expression compared with line A. (J:197654)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
