Mobilization of the transposon from Tn(sb-SBlac)C.176599bFsp transgenic mice with Sleeping Beauty transposase from an unidentified line of Tg(Prm1-sb16)Fsp transgenic mice results in the integration of the transposon into chromosome 2 at position 74627958-74628736 5' of Mtx2. The transposon consists of a human beta globin minimal promoter driven lacZ reported gene and a loxP site placed between the sleeping beauty inverted terminal repeats. LacZ expression is detected in the digestive, neural tube and somites of E11.5 embryos. (J:199174)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Transposon induced
Transposon insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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