An FRT flanked neomycin resistance cassette followed by a loxP site was inserted in intron 3 and a second loxP site was inserted following exon 4. The neo selection cassette was subsequently removed from properly targeted mice by crossing to mice ubiquitously expressing flp recombinase. (J:202810)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count