A targeting vector was designed to insert loxP sites on either side of exon 2 followed by an FRT-flanked neomycin selection cassette. The neomycin resistance cassette was removed by Flpe-mediated recombination using mice carrying the Tg(CAG-Flpe)2Arte allele. (J:202737)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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