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The "multiple lox" MADM-ML-11 targeting vector has a CMV enhancer/chicken beta-actin core promoter (pCA) upstream of the "GT MADM-ML" cassette. The "GT MADM-ML" cassette is designed with the N-terminal portion of a mutant enhanced green fluorescent protein (mut4-EGFP; nucleotide 1-273), a beta-globin intronic sequence (containing an frt-lox5171-lox2272-frt-loxP-Neo-loxP), the C-terminal portion of a red fluorescent protein (tdTomato; nucleotide 4-1544) tagged with three copies of the Myc epitope at its C-terminus, and an SV40 T-antigen poly(A) signal. (J:101977, J:202665)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
