A loxP site followed by an FRT flanked neomycin resistance cassette was inserted 5' of the second coding exon and a second loxP site was inserted downstream of this exon. Flp recombinase expression in properly targeted mice excised the selection cassette leaving the second coding exon flanked by loxP sites. (J:197393)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count