A conditional mutation was generated by insertion of a loxP site upstream of exon 2 and a loxP- and FRT-flanked neomycin resistance cassette. Recombination removed the selection cassette.
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count