Chr 16 contains a ~10.0 Mb duplication generated in ES cells by Cre-mediated recombination between loxP sites that had been introduced into Hspa13 (formerly Stch) and App by homologous recombination using targeting vectors from the Mutagenic Insertion and Chromosome Engineering Resource (MICER). (J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
Duplication
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--
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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