An FRT site flanked neomycin resistance gene cassette and a loxP site were inserted into intron 3. A second loxP site was inserted into intron 4. Flp-mediated recombination removed the neo cassette and left exon 4 floxed. (J:198940)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count