Recombinase mediated cassette exchange replaced the hygromycin resistance casssette in Gt(ROSA)26Sortm1Rkuhn with a neomycin resistance cassette, polyadenylation sequence, FRT site and a C-terminally V5-tagged human cDNA lacking the mitochondrial leader sequence (-MLS; FHcys) with a polyadenylation sequence driven by a CAG promoter. (J:198486)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count