The TGT cysteine codon of the CaaX motif was changed to a TCT serine codon. In addition, a floxed neo resistance cassette was introduced 1.5 kb downstream of the point mutation. (J:197315)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count