The transgene contains a CAG promoter driving ubiquitous expression of the human cDNA. Cre-mediated recombination removed a floxed neomycin resistance cassette inserted between the promoter and cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. The #a line reflects the cre-recombined transgene while the unrecombined transgene is referred to as line #. (J:143385)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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