The transgene contains a CAG promoter driving ubiquitous expression of the human cDNA. Cre-mediated recombination removed a floxed neomycin resistance cassette inserted between the promoter and cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. The #a line reflects the cre-recombined transgene while the unrecombined transgene is referred to as line #. (J:143385)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count