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The transgene was generated via lentitransgenesis; a self-inactivating lentiviral vector was designed with 105 N-terminal residues of the Cyclin B1 (Ccnb1) gene (harboring the APC/C ubiquitination site responsible for its specific degradation in G0/G1 cells) and an enhanced green fluorescence protein (EGFP) sequence under control of a constitutive mouse phosphoglycerate kinase 1 (Pgk1) promoter. Line 1 was generated. (J:188998)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
