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The insertion of a transgene containing a 4.1kb tyrosinase mini gene under the control of the tyrosinase promoter in line Bart97b produced a 11kb deletion spanning 6 exons (chr17:17,848,861-17,849,039 based on the GRCm38/mm10 assembly). RT-PCR confirmed complete absence of RNA transcripts in homozygous testis. (J:216863)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
