An HPRT cassette with a 3' lox66 site was inserted upstream of exon 2. A lox71 site was inserted downstream of exon 2. Cre-mediated recombination is required to invert exon 2 and inactivate the gene. (J:198588)
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An HPRT cassette with a 3' lox66 site was inserted upstream of exon 2. A lox71 site was inserted downstream of exon 2. Cre-mediated recombination is required to invert exon 2 and inactivate the gene. (J:198588)