A loxP-flanked hygromycin resistance cassette was inserted into intron 1 and a third loxP site into intron 3. Cre-mediated recombination excised the selection cassette, leaving exons 2 and 3 of the gene flanked by a pair of loxP sites. (J:119296)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count