A mouse Il21 cDNA was placed under the control of the H2-Kb promoter and the Ig enhancer. Thirty-one independent founder lines were produced. Two groups were identified based on length of survival. The original paper analysed mice from founder lines surviving longer than three weeks. (J:126318)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count