The following elements were inserted into the mouse Fzd3 (frizzled homolog 3 (Drosophila)) locus via homologous recombination: a loxP site in intron 2, a 3HA (hemagglutinin) epitope in the coding region between the cysteine-rich domain and the first transmembrane domain, a loxP site in intron 3, and an Frt-flanked PGK-neo cassette. The neomycin cassette was removed by germline Flp-mediated recombination. (J:101977, J:207894)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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