A loxP site was inserted downstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site and a EGFP with a splice acceptor was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed. (J:201118)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count