Gt(ROSA)26Sor^{tm2(Pik3ca*)Dsa}

The targeting construct inserted into the locus an FRT site, floxed neomycin resistance cassette with 4 polyadenylation sequences, a cDNA encoding a constitutively active form of Pik3ca with an amino acid substitution of arginine for histidine at position 1047 (H1047R), a polyadenyation sequence and an FRT site. Cre-mediated recombination is required to achieve expression. (J:197054)