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The entire coding region was replaced by a floxed PGK-neomycin selection cassette. The selection cassette was then removed from properly targeted mice by cre excision. Absence of transcription was confirmed by rtPCR and loss of protein by immunofluorescein staining. (J:200968)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
