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The cre recombinase coding region fused to the sequence for a mutated ligand-binding domain of the human estrogen receptor was inserted into a construct where it is under the control of the 500 bp brachyury (T) promoter. Eight transgenic lines were generated and one showed extensive cre activity in presence of tamoxifen but little without tamoxifen induction. (J:200549)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
