A targeting vector, obtained from EUCOMM, containing a FRT site flanked beta-geo cassette and a loxP site was inserted upstream of exon 3. A second loxP site was inserted downstream of exon 3. ES cells were transiently transfected with a FLP recombinase vector to remove the selection cassette. (J:188485)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count