An IRES-cre/ERT2-Frt-PGKneo-Frt cassette was inserted into the Runx3 gene just downstream of the stop codon in exon 6. Germline mutants were crossed to Flp expressing mice to remove the neo marker. (J:197913)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count