The cre recombinase open reading frame was inserted into exon 1 at the translation initiation codon of the murine Rax gene in a BAC (RP24-82D21), using recombineering methods. The modified BAC was purified and used for pronuclear injection. Three founders were produced and one was chosen for further analysis. (J:198990)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count